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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Nuclear factor erythroid 2-related factor 2 |
Synonyms: | HEBP1, NF-E2-related factor 2, NFE2-related factor 2, NFE2L2, NRF2, Nrf-2 |
Immunogen: | Recombinant protein corresponding to Human NRF2 |
Uniprot ID: | Q16236 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 67 kDa / 90-110 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 800 | C6, C2C12, HepG2 |
Background
NRF2, also named as NFE2L2, belongs to the bZIP family and CNC subfamily. It is a transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. NRF2 is important for the coordinated up-regulation of genes in response to oxidative stress. It may be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
Images
| WB analysis of NRF2(GB115673). |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |