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Anti-Natriuretic peptide receptor B Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Natriuretic peptide receptor B rabbit polyclonal antibody |
Gene Name: | Atrial natriuretic peptide receptor 2 |
Synonyms: | Atrial natriuretic peptide receptor type B, ANP-B, ANPR-B, NPR-B, Guanylate cyclase B, GC-B, Npr2, AMDM, GUC2B |
Immunogen: | Recombinant protein corresponding to Mouse Natriuretic peptide receptor B |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | P20594, Q6VVW5, P16067 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 700-1: 2100 | small intestine |
Background
NPR2, also named as ANPRB, GC-B, NPR-B, ANPR-B and ANP-B, belongs to the adenylyl cyclase class-4/guanylyl cyclase family. It is a receptor for the C-type natriuretic peptide NPPC/CNP hormone. NRP2 has guanylate cyclase activity upon binding of its ligand. It may play a role in the regulation of skeletal growth. NPR2 is the primary receptor for C type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Defects in NPR2 are the cause of acromesomelic dysplasia Maroteaux type (AMDM).
Images
| Immunohistochemistry of paraffin embedded mouse small intestine using NPR2 (GB111852) at dilution of 1:700 (300x lens) |
| Immunohistochemistry of paraffin embedded rat small intestine using NPR2 (GB111852) at dilution of 1:700 (300x lens) |
| Immunofluorescence of paraffin embedded mouse small intestine using NPR2 (GB111852) at dilution of 1:700 (300x lens) |
| Immunofluorescence of paraffin embedded rat small intestine using NPR2 (GB111852) at dilution of 1:700 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |