| Reactivity: | R | 
| Applications: | IHC/IF | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Gene Name: | Nephrin  | 
Synonyms:  | NPHS1, CNF, NPHN, nephrin, NPHS1 nephrin, nephrin  | 
Immunogen:  | KLH conjugated Synthetic peptide corresponding to Rat nephrin  | 
Uniprot ID:  | Q9R044  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Subcellular location:  | Cell membrane  | 
Predicted MW. / Observed MW.  | 134 kDa / 165-200 kDa  | 
Product Usage Information
IHC/IF  | Rat  | 1: 1000-1: 2000  | kidney  | 
Background
Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.
Images
  | IHC analysis of Nephrin(GB115655).  | 
  | IHC analysis of Nephrin(GB115655).  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |