| Reactivity: | H | 
| Applications: | IHC/IF | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Gene Name: | Nestin  | 
Synonyms:  | NES, Nbla00170, nestin  | 
Immunogen:  | KLH conjugated Synthetic peptide corresponding to Human Nestin  | 
Uniprot ID:  | P48681  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Subcellular location:  | Cytoplasm, intermediate filament cytoskeleton  | 
Product Usage Information
IHC/IF  | Human  | 1: 500-1: 1000  | glioblastoma multiforme, kidney  | 
Background
Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
Images
  | IHC analysis of Nestin(GB115685).  | 
  | IHC analysis of Nestin(GB115685).  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |