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| Reactivity: | H & H,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | OAS3 rabbit polyclonal |
Gene Name: | 2'-5'-oligoadenylate synthase 3 |
Synonyms: | (2 5)oligo(A) synthase 3, 2 5A synthase 3, 2',5'-oligoadenylate synthetase-like 10, 2 5'LIGO, oasl10, OAS3, p100, p100 OAS, p100OAS |
Immunogen: | Recombinant protein corresponding to Mouse OAS3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 126 kDa |
Observed MW. | 126 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | A375 |
IHC | Human, Rat | 1: 2000-1: 4000 | tonsil, colon |
Background
The 2-prime,5-prime oligoadenylate synthetases (OASs), such as OAS3, are interferon-induced proteins characterized by their capacity to catalyze the synthesis of 2-prime,5-prime oligomers of adenosine (2-5As). It is also named as p100 OAS and belongs to the 2-5A synthase family. OAS3 is involved in inhibition of cellular protein synthesis and in viral infection resistance. This antibody may have weak cross-reaction with OAS1 protein due to the highly homology.
Images
| Western blot analysis of OAS3 (GB113596) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded human tonsil using OAS3 (GB113596) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded rat colon using OAS3 (GB113596) at dilution of 1: 4000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |