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| Reactivity: | H & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | OPA3 rabbit polyclonal antibody |
Gene Name: | Optic atrophy 3 protein |
Synonyms: | OPA3, MGA3, Optic atrophy 3 (Iraqi Jewish 'optic atrophy plus'), Optic atrophy 3 |
Immunogen: | Recombinant protein corresponding to Human OPA3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion |
Predicted MW. | 20 kDa |
Observed MW. | 20 kDa |
Uniprot ID: | Q9H6K4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 200-1: 400 | HeLa, Jurkat, 293T, A549, K562 |
IHC/IF | Human, Mouse, Rat | 1: 700-1: 1400 | gastric cancer, stomach |
Background
The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene.
Images
| Western blot analysis of OPA3 (GB112548) at dilution of 1: 200 |
| Immunofluorescence of paraffin embedded human gastric cancer using OPA3 (GB112548) at dilution of 1: 700 (350x lens) |
| Immunofluorescence of paraffin embedded mouse stomach using OPA3 (GB112548) at dilution of 1: 700 (300x lens) |
| Immunofluorescence of paraffin embedded rat stomach using OPA3 (GB112548) at dilution of 1: 700 (350x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |