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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | OS9 rabbit polyclonal antibody |
Gene Name: | Protein OS-9 |
Synonyms: | Amplified in osteosarcoma 9, OS9 |
Immunogen: | Recombinant protein corresponding to Human OS9 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 76 kDa |
Observed MW. | 65 kDa |
Uniprot ID: | Q13438 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 1000-1: 2000 | HeLa, K562, MCF-7 |
Background
OS-9 is a ubiquitously expressed ensoplasmic reticulum (ER)-associated protein originally identified as being amplified in certain osteosarcomas. It functions in ER quality control and ER-associated degradation (ERAD). There are three isoforms of this protein: OS-9.1, OS-9.2 and OS-9.3. The longest isoform, OS-9.1, contains 667 aa, OS-9.2 lacks aa 535-589, whereas OS-9.3 lacks aa 456-470 and 535-589. OS-9.1 and OS-9.2 are N-glycosylated, ubiquitously expressed in human tissues, and amplified in tumors. Isoform 2 is the major isoform detected in all cell types examined. This antibody can recognize all three isoforms of OS-9.
Images
 | Western blot analysis of OS9 (GB112923) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |