| Reactivity: | M,R | 
| Applications: | WB | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Gene Name: | Protein disulfide-isomerase A5  | 
Synonyms:  | PDIA5, PDIR, Protein disulfide isomerase A5  | 
Immunogen:  | Recombinant protein corresponding to Mouse PDIA5  | 
Uniprot ID:  | Q921X9  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Predicted MW. / Observed MW.  | 60 kDa / 60 kDa  | 
Product Usage Information
WB  | Mouse, Rat  | 1: 500-1: 1000  | pancreas  | 
Background
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. The N-terminal TRX-like domain is the primary binding site for the major ER chaperone calreticulin and possibly other proteins and substrates as well. Alternative splicing results in multiple protein- and non-protein-coding transcript variants.
Images
  | Western blot analysis of PDIA5 (GB114208) at dilution of 1: 1000  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |