| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PGE2 receptor EP4 subtype rabbit polyclonal antibody |
Gene Name: | Prostaglandin E2 receptor EP4 subtype |
Synonyms: | PGE receptor EP4 subtype, Prostanoid EP4 receptor, PTGER4, PTGER2, EP4R |
Immunogen: | Recombinant protein corresponding to Mouse PGE2 receptor EP4 subtype |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | P35408 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 500-1: 1000 | colon cancer, placenta |
Background
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
Images
| Immunohistochemistry of paraffin embedded human colon cancer using PE2R4 (GB111814) at dilution of 1:500 (400x lens) |
| Immunohistochemistry of paraffin embedded human placenta using PE2R4 (GB111814) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |