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Anti-PPP2R4 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PPP2R4 rabbit polyclonal |
Gene Name: | Serine/threonine-protein phosphatase 2A activator |
Synonyms: | Phosphotyrosyl phosphatase activator, PTPA, Ppp2r4, PR53, PP2A subunit B' isoform PR53, PP2A |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PPP2R4 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 37kDa |
Observed MW. | 37kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 300-1: 1000 | brain, testis |
Background
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Images
| Western blot analysis of PTPA (GB113796) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |