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Anti-Phospho-IRS1 (Ser307) Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Insulin receptor substrate 1 |
Synonyms: | HIRS 1, IRS 1, IRS1, IRS-1, P-IRS1 |
Immunogen: | KLH conjugated Synthetic phosphopeptide corresponding to Human IRS1(Ser307） |
Uniprot ID: | P35568 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 132 kDa / 180 kDa |
Product Usage Information
WB | Human | 1: 300-1: 600 | 293 |
Background
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
Images
| Western blot analysis of Phospho-IRS1(Ser307) (GB115456) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |