| Reactivity: | H,M | 
| Applications: | WB | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Full Name: | Plxdc2 rabbit polyclonal  | 
Gene Name:  | Plexin domain-containing protein 2  | 
Synonyms:  | Tumor endothelial marker 7-related protein, Plxdc2, Tem7r, plexin domain containing 2, FLJ14623  | 
Immunogen:  | KLH conjugated Synthetic peptide corresponding to Mouse Plxdc2  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Predicted MW.  | 60 kDa  | 
Observed MW.  | 60 kDa  | 
Uniprot ID:  | 
Product Usage Information
Applications  | Species  | Dilution  | Positive tissue  | 
WB  | Human, Mouse  | 1: 1000-1: 2000  | lung, skin  | 
Background
PLXDC2 (Plexin-domain containing 2), also named tumor endothelial marker 7-related protein (TEM7R), is a single-pass type I membrane protein with some homology to nidogen and to plexins. PLXDC2 is located in tumor endothelium and plays a role in tumor angiogenesis. Three isoforms of PLXDC2 produced by alternative splicing have been described. Recent finding revealed that PLXDC2 is a mitogen for neural progenitors and functions as a novel regulator of the development of different brain regions, suggesting its role in coordinating proliferation and differentiation in the developing nervous system.
Images
![]()  | Western blot analysis of Plxdc2 (GB113508) at dilution of 1: 2000  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |