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| Reactivity: | H,M,R & R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SBDS rabbit polyclonal |
Gene Name: | Ribosome maturation protein SBDS |
Synonyms: | CGI-97, SBDS, SDS, SWDS, Protein 22A3, Shwachman Bodian Diamond syndrome protein |
Immunogen: | Recombinant protein corresponding to Mouse SBDS |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 29 kDa |
Observed MW. | 29 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 800-1: 1500 | pancreas, kidney |
IHC | Rat | 1: 1000-1: 2000 | kidney |
Background
Shwachman-Bodian-Diamond syndrome (SBDS) is a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The protein may function in RNA metabolism. Mutations within its gene are associated with Shwachman-Bodian-Diamond syndrome.This gene encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. This gene has a closely linked pseudogene that is distally located.
Images
| Western blot analysis of SBDS (GB113594) at dilution of 1: 1500 |
| Immunohistochemistry analysis of paraffin-embedded rat kidney using SBDS (GB113594) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |