| Reactivity: | H,M,R | 
| Applications: | WB | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Gene Name: | SEC14-like protein 2  | 
Synonyms:  | C22orf6, KIAA1186, KIAA1658, SPF, TAP, TAP1, SEC14L2  | 
Immunogen:  | Recombinant protein corresponding to Mouse SEC14L2/TAP  | 
Uniprot ID:  | Q99J08  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Predicted MW. / Observed MW.  | 46 kDa / 45 kDa  | 
Product Usage Information
WB  | Human, Mouse, Rat  | 1: 500-1: 1500  | liver  | 
Background
Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell (By similarity).
Images
  | Western blot analysis of SEC14L2 (GB114152) at dilution of 1: 1000  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |