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Anti-SEL1L Rabbit pAb (100 μl)
| Reactivity: | H,M & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SEL1L rabbit polyclonal antibody |
Gene Name: | Protein sel-1 homolog 1 |
Synonyms: | IBD2, PRO1063, Sel 1 like protein, Sel 1 suppressor of lin 12 like, Sel-1L, SEL1 LIKE, Sel1l, Suppressor of lin-12-like protein 1, UNQ128, UNQ128/PRO1063, TSA305 |
Immunogen: | Recombinant protein corresponding to Mouse SEL1L |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Endoplasmic reticulum membrane |
Predicted MW. | 88 kDa |
Observed MW. | 110 kDa |
Uniprot ID: | Q9Z2G6 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 1000-1: 2000 | MCF7, NIH/3T3 |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1500 | pancreas |
Background
Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins . Enhances SYVN1 stability . Plays a role in LPL maturation and secretion . Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells . May play a role in Notch signaling.
Images
| Western blot analysis of SEL1L (GB114116) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human pancreas using SEL1L (GB114116) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse pancreas using SEL1L (GB114116) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat pancreas using SEL1L (GB114116) at dilution of 1: 1000 |
| Immunofluorescence of paraffin embedded human pancreas using SEL1L (GB114116) at dilution of 1: 1000 |
| Immunofluorescence of paraffin embedded mouse pancreas using SEL1L (GB114116) at dilution of 1: 1000 |
| Immunofluorescence of paraffin embedded rat pancreas using SEL1L (GB114116) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |