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| Reactivity: | H & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SIX1 rabbit polyclonal antibody |
Gene Name: | Homeobox protein SIX1 |
Synonyms: | Sine oculis homeobox homolog 1, Six1, TIP39, BOS3, SIX homeobox 1 |
Immunogen: | Recombinant protein corresponding to Mouse SIX1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. | 32 kDa |
Observed MW. | 36 kDa |
Uniprot ID: | Q62231 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | 293T, PC-3, HepG2 |
IHC/IF | Human, Mouse, Rat | 1: 600-1: 3000 | breast cancer, lung, Skeletal muscle |
Background
The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3).
Images
| Western blot analysis of SIX1 (GB112291) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded human breast cancer using SIX1 (GB112291) at dilution of 1: 650 (400x lens) |
| Immunohistochemistry of paraffin embedded human lung using SIX1 (GB112291) at dilution of 1: 650 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse lung using SIX1 (GB112291) at dilution of 1: 650 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse skeletal muscle using SIX1 (GB112291) at dilution of 1: 650 (400x lens) |
| Immunohistochemistry of paraffin embedded rat lung using SIX1 (GB112291) at dilution of 1: 650 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat skeletal muscle using SIX1 (GB112291) at dilution of 1: 650 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse lung using SIX1 (GB112291) at dilution of 1: 650 (400x lens) |
| Immunofluorescence of paraffin embedded mouse skeletal muscle using SIX1 (GB112291) at dilution of 1: 650 (400x lens) |
| Immunofluorescence of paraffin embedded rat lung using SIX1 (GB112291) at dilution of 1: 650 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |