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| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Small conductance calcium-activated potassium channel protein 1 |
Synonyms: | hSK1, KCa2.1, KCNN1, SK, SK1, SKCa 1, SKCA1 |
Immunogen: | Recombinant protein corresponding to Mouse SK1 |
Uniprot ID: | Q9EQR3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane |
Predicted MW. / Observed MW. | 59 kDa / 70 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 2000-1: 3000 | brain, kidney, liver |
IHC/IF | Mouse, Rat | 1: 1200-1: 2400 | brain |
Background
Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization.
Images
| Western blot analysis of KCNN1 (GB115362) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin embedded mouse Brain using KCNN1 (GB115362) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin embedded rat Brain using KCNN1 (GB115362) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |