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Anti-STEAP3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | STEAP3 rabbit polyclonal antibody |
Gene Name: | Metalloreductase STEAP3 |
Synonyms: | Dudulin-2, Protein nm1054, Six-transmembrane epithelial antigen of prostate 3, Tumor suppressor-activated pathway protein 6, Steap3, Tsap6,1010001D01Rik, MGC93147, pHyde |
Immunogen: | Recombinantproteincorrespondingto Mouse STEAP3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Endosome |
Uniprot ID: | Q8CI59 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 1500 | liver, pancreas |
Background
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
Images
| Immunohistochemistry of paraffin embedded mouse liver using STEA3 (GB111656) at dilution of 1:700 (300x lens) |
 | Immunohistochemistry of paraffin embedded mouse pancreas using STEA3 (GB111656) at dilution of 1:700 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |