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Anti-TBLR1/TBL1XR1 Rabbit pAb (100 μl)
| Reactivity: | M,R & H |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TBLR1/TBL1XR1 rabbit polyclonal |
Gene Name: | F-box-like/WD repeat-containing protein TBL1XR1 |
Synonyms: | C21, DC42, IRA1, TBL1 related protein 1, TBL1XR1, TBLR1,Transducin (beta) like 1 X linked receptor 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TBLR1/TBL1XR1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 56 kDa |
Observed MW. | 56 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | brain |
IHC | Human | 1: 700-1: 1400 | colon cancer, kidney |
Background
TBLR1 is an F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. It plays an essential role in transcription activation mediated by nuclear receptors and probably acts as an integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteosomal degradation of the N-Cor complex, thereby allowing cofactor exchange, and transcription activation.
Images
| Western blot analysis of TBL1XR1 (GB113549) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded human colon cancer using TBL1XR1 (GB113549) at dilution of 1: 1400 |
| Immunohistochemistry analysis of paraffin-embedded human kidney using TBL1XR1 (GB113549) at dilution of 1: 1400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |