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| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TLR2 rabbit polyclonal |
Gene Name: | Toll-like receptor 2 |
Synonyms: | CD282, TIL4, TLR2, toll like receptor 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to mouse TLR2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 90 kDa |
Observed MW. | 90-105 kDa |
Uniprot ID: | Q9QUN7 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 200-1: 500 | spleen, lung |
Background
TLR2, also known as CD282, is a member of the Toll-like receptor (TLR) family. TLR receptors are type I integral transmembrane glycoproteins which play a fundamental role in pathogen recognition and activation of innate immunity. TLR2 is expressed by immune cells including monocytes/macrophages, polymorphonuclear leukocytes (PMLs) and dendritic cells, and is also expressed by some no-immune cells including endothelial and epithelial cells . TLR2 forms heterodimers with TLR1 and TLR6, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive immunity to pathogens and protection from immune sequelae related to infection with these pathogens .
Images
 | Western blot analysis of TLR2 (GB113504) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |