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Anti-TMEM199 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TMEM199 rabbit polyclonal |
Gene Name: | Transmembrane protein 199 |
Synonyms: | Tmem199, C17orf32, RE40914p |
Immunogen: | Recombinant protein corresponding to Mouse TMEM199 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 23 kDa |
Observed MW. | 23 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 2000-1: 4000 | spleen, stomach, testis |
Background
TMEM199, also named as C17orf32, is a component of the complex sense antisense architecture (CSAGA).Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation . May be involved in Golgi homeostasis.
Images
 | Western blot analysis of TMEM199 (GB112790) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |