| Reactivity: | M,R | 
| Applications: | WB | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Full Name: | Ube2L6 rabbit polyclonal antibody  | 
Gene Name:  | Ubiquitin/ISG15-conjugating enzyme E2 L6  | 
Synonyms:  | E2 ubiquitin-conjugating enzyme L6, UbcM8, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6, Ube2l6, Ubce8  | 
Immunogen:  | Recombinant protein corresponding to Mouse Ube2L6  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Predicted MW.  | 18 kDa  | 
Observed MW.  | 18 kDa  | 
Uniprot ID:  | Q9QZU9, Q4V8J2  | 
Product Usage Information
Applications  | Species  | Dilution  | Positive tissue  | 
WB  | Mouse, Rat  | 1: 500-1: 1000  | liver, spleen, lung  | 
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.
Images
![]()  | Western blot analysis of UBE2L6 (GB112731) at dilution of 1: 500  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |