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Anti-WBSCR16 Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | WBSCR16 rabbit polyclonal |
Gene Name: | RCC1-like G exchanging factor-like protein |
Synonyms: | RCC1-like, Williams-Beuren syndrome chromosomal region 16 protein homolog, Rcc1l, Wbscr16 |
Immunogen: | Recombinant protein corresponding to Mouse WBSCR16 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 50 kDa |
Observed MW. | 50 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 1000-1: 2000 | kidney |
Background
Guanine nucleotide exchange factor (GEF) for mitochondrial dynamin-related GTPase OPA1. Activates OPA1, by exchanging bound GDP for free GTP, and drives OPA1 and MFN1-dependent mitochondrial fusion . Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
Images
 | Western blot analysis of RCC1L (GB112914) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |