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Anti-ZC3H8 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Zinc finger CCCH domain-containing protein 8 |
Synonyms: | Fliz1, ZC3H8, ZC3HDC8 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ZC3H8 |
Uniprot ID: | Q9JJ48 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 35 kDa / 35 kDa |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human | 1: 300-1: 600 | Hela, 293T |
Background
Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Acts as a transcriptional repressor of the GATA3 promoter. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis (By similarity). Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene.
Images
| WB analysis of ZC3H8(GB115641). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 500, 4°C overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 3000, RT, 1h. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |