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Anti-Shoc2 / Sur8 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Shoc2 / Sur8 rabbit polyclonal |
Gene Name: | Leucine-rich repeat protein SHOC-2 |
Synonyms: | Protein soc-2 homolog, Protein sur-8 homolog, Shoc2, Ras-binding protein Sur-8, KIAA0862 |
Immunogen: | Recombinant protein corresponding to Mouse Shoc2 / Sur8 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human | 1: 2000-1: 4000 | colon, stomach |
Background
Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.
Images
| Immunohistochemistry analysis of paraffin-embedded human colon using Sur8 (GB112779) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded human stomach using Sur8 (GB112779) at dilution of 1: 4000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |