| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Sp7 / Osterix rabbit polyclonal antibody |
Gene Name: | Transcription factor Sp7 |
Synonyms: | C22, Zinc finger protein osterix, Sp7, Osx, Osterix, Sp7 transcription factor |
Immunogen: | Recombinant protein corresponding to Mouse Sp7 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q8VI67 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 200-1: 1000 | bone injury, embryonic mouse, embryonic rat |
Background
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.
Images
| Immunohistochemistry of paraffin embedded mouse bone injury using SP7 (GB111900) at dilution of 1:200 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse embryonic mouse using SP7 (GB111900) at dilution of 1:200 (400x lens) |
| Immunohistochemistry of paraffin embedded rat embryonic rat using SP7 (GB111900) at dilution of 1:200 (400x lens) |
![]() | Immunohistochemistry of paraffin embedded rat embryonic rat using SP7 (GB111900) at dilution of 1:300 (400x lens) |
| Immunofluorescence of paraffin embedded mouse embryonic mouse using SP7 (GB111900) at dilution of 1:500 (400x lens) |
| Immunofluorescence of paraffin embedded rat embryonic rat using SP7 (GB111900) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |