Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: |
Superoxide Dismutase 1 rabbit polyclonal |
Gene Name: |
Superoxide dismutase [Cu-Zn] |
Synonyms: |
ALS, ALS1, HEL-S-44, IPOA, SOD, hSod1, homodime |
Immunogen: |
KLH conjugated Synthetic peptide corresponding to Mouse SOD1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: |
Cytoplasm,Mitochondrion,Nucleus |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1:300-1:600 | liver,brain |
IF | Human, Mouse, Rat | 1:300-1:600 | liver,brain |
Background
SOD1 binds copper and zinc ions and is one of three superoxide dismutases responsible for destroying freesuperoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic and mitochondrial intermembrane space protein, acting as a homodimer to convert naturally occurring, but harmful, superoxide radicals to molecular oxygen and hydrogen peroxide.Hydrogen peroxide can then be broken down by another enzyme called catalase.
Images
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Immunohistochemistry analysis of paraffin-embedded human liver using SOD1 (GB11263) at dilution of 1:300 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using SOD1 (GB11263) at dilution of1:600 |
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Immunohistochemistry analysis of paraffin-embedded mouse liver using SOD1 (GB11263) at dilution of 1: 1:300 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |