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Anti-Syndecan-1/CD138 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Syndecan-1 |
Synonyms: | CD138, CD138/Syndecan-1, SDC, SDC1, SYND1, syndecan, syndecan 1 |
Immunogen: | Recombinant protein corresponding to Human Cd138 |
Uniprot ID: | P18827 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 100-1: 400 | tonsil, esophagus, esophageal cancer, colon, oral epithelium, urinary bladder |
Background
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Images
| Immunohistochemistry analysis of paraffin embedded human tonsil using CD138 (GB115052) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded human esophagus using CD138 (GB115052) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded human esophageal cancer using CD138 (GB115052) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded human colon using CD138 (GB115052) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded mouse model of antigen stimulation spleen using CD138 (GB115052) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin embedded mouse urinary bladder using CD138 (GB115052) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin embedded rat esophagus using CD138 (GB115052) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin embedded rat oral epithelium using CD138 (GB115052) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin embedded rat urinary bladder using CD138 (GB115052) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |