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Anti-TBC1D5 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TBC1D5 rabbit polyclonal |
Gene Name: | TBC1 domain family member 5 |
Synonyms: | Tbc1d5, KIAA0210 |
Immunogen: | Recombinant protein corresponding to Mouse TBC1D5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 92 kDa |
Observed MW. | 92 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 2000-1: 4000 | stomach, kidney, lymph |
Background
May act as a GTPase-activating protein for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol; at least retromer displacement seems to require its catalytic activity. Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN); the function seems to require its catalytic activity. Involved in regulation of autophagy. May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy induction.
Images
 | Western blot analysis of TBCD5 (GB112802) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |