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| Reactivity: | Mouse, Rat |
| Applications: | IHC, ELISA |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Polyclonal antibody |
| Gene Name: | transcription factor Dp-1 |
| Gene Symbol: | TFDP1 |
| Synonyms: | DP1; DILC; Dp-1; DRTF1; DP1/TFDP1 |
| Gene ID: | 7027 |
| UniProt ID: | Q14186 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human DP1/DP1/TFDP1 (NP_009042.1). |
| Dilution: | IHC 1:50-1:200 |
| Purification Method: | Affinity purification |
| Concentration: | 0.51 mg/ml |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-TFDP1 antibody |
Background
This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.
Images
 | Immunohistochemistry analysis of paraffin-embedded Rat testis using DP1/TFDP1 Rabbit pAb (A14789) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining. |
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