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| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | Unconjugated |
| Gene Name: | TNF receptor superfamily member 10d |
| Gene Symbol: | TNFRSF10D |
| Synonyms: | DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4 |
| Gene ID: | 8793 |
| UniProt ID: | Q9UBN6 |
| Clone ID: | 3I6F5 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 56-211 of human TNFRSF10D/TRAILR4 (NP_003831.2). |
| Dilution: | FC,1:500 - 1:1000 |
| Purification Method: | Affinity purification |
| Concentration: | 1.13 mg/mL |
| Buffer: | PBS with 0.05% proclin300,0.05% BSA,50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-TNFRSF10D Antibody |
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis.
Images
 | Flow cytometry: 1×10^6 293F cells (Low Expression,left) and 293F (Transfection,right) cells were surface-stained with TNFRSF10D/TRAILR4 Rabbit mAb (A24976,2 μg/mL,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line), followed by Alexa Fluor® 647 conjugated goat anti-rabbit pAb staining. Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 293F (Transfection) cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or TNFRSF10D/TRAILR4 Rabbit mAb (A24976,2 μg/mL,right). |
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