| Reactivity: | M,R & M,R | 
| Applications: | WB & IHC/IF | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Full Name: | TPPP rabbit polyclonal antibody  | 
Gene Name:  | Tubulin polymerization-promoting protein  | 
Synonyms:  | 25 kDa brain specific protein, p24, p25, p25 alpha, p25alpha, TPPP, TPPP/p25, TPPP1  | 
Immunogen:  | KLH conjugated Synthetic peptide corresponding to Mouse TPPP  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Subcellular location:  | Golgi outpost Cytoplasm, cytoskeleton  | 
Predicted MW.  | 24 kDa  | 
Observed MW.  | 24 kDa  | 
Uniprot ID:  | Q7TQD2  | 
Product Usage Information
Applications  | Species  | Dilution  | Positive Sample  | 
WB  | Mouse, Rat  | 1: 1000-1: 2000  | brain, cerebellum  | 
IHC/IF  | Mouse, Rat  | 1: 1000-1: 2000  | spinal marrow, brain  | 
Background
TPPP, also named as TPPP1, P24 and P25, belongs to the TPPP family. TPPP promotes in vitro the polymerization of tubulin into double-walled tubules and polymorphic aggregates or bundled stabilized microtubules blocks. When overexpressed, TPPP inhibits mitotic spindle assembly and nuclear envelope breakdown, apparently without affecting other cellular events.
Images
![]()  | Western blot analysis of TPPP (GB114047) at dilution of 1: 1000  | 
![]()  | Immunohistochemistry of paraffin embedded mouse brain using TPPP (GB114047) at dilution of 1: 1000  | 
![]()  | Immunohistochemistry of paraffin embedded rat brain using TPPP (GB114047) at dilution of 1: 1000  | 
![]()  | Immunohistochemistry of paraffin embedded mouse spinal marrow using TPPP (GB114047) at dilution of 1: 1000  | 
![]()  | Immunofluorescence of paraffin embedded mouse brain using TPPP (GB114047) at dilution of 1: 1000  | 
![]()  | Immunofluorescence of paraffin embedded rat brain using TPPP (GB114047) at dilution of 1: 1000  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |