Reactivity: | Human |
Applications: | WB, ELISA |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Polyclonal antibody |
Gene Name: | tRNA aspartic acid methyltransferase 1 |
Gene Symbol: | TRDMT1 |
Synonyms: | DMNT2; DNMT2; PUMET; RNMT1; MHSAIIP; TRDMT1 |
Gene ID: | 1787 |
UniProt ID: | O14717 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 192-391 of human TRDMT1 (NP_004403.1). |
Dilution: | WB 1:1000-1:2000 |
Purification Method: | Affinity purification |
Concentration: | 1.64 mg/ml |
Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-TRDMT1 antibody |
Background
This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa.
Images
![]() | Western blot analysis of various lysates using TRDMT1 Rabbit pAb (A10535) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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