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| Reactivity: | Human, Mouse, Rat |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Clonality: | Polyclonal antibody |
| Gene Name: | tRNA splicing endonuclease subunit 54 |
| Gene Symbol: | TSEN54 |
| Synonyms: | PCH4; PCH5; PCH2A; sen54; SEN54L; TSEN54 |
| Gene ID: | 283989 |
| UniProt ID: | Q7Z6J9 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TSEN54 (NP_997229.2). |
| Dilution: | WB 1:500-1:2000 |
| Purification Method: | Affinity purification |
| Concentration: | 2.52 mg/ml |
| Buffer: | Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-TSEN54 antibody |
Background
This gene encodes a subunit of the tRNA splicing endonuclease complex, which catalyzes the removal of introns from precursor tRNAs. The complex is also implicated in pre-mRNA 3-prime end processing. Mutations in this gene result in pontocerebellar hypoplasia type 2.
Images
 | Western blot analysis of various lysates using TSEN54 Rabbit pAb (A15227) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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