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| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TWF2 rabbit polyclonal |
Gene Name: | Twinfilin-2 |
Synonyms: | A6-related protein, mA6RP, Twinfilin-1-like protein, Twf2, Ptk9l, MSTP011, A6RP, A6r |
Immunogen: | Recombinant protein corresponding to Mouse TWF2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 39 kDa |
Observed MW. | 39 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse | 1: 500-1: 1000 | lymph node, thymus |
Background
TWF2 (Twinfilin 2) was identified by its interaction with the catalytic domain of protein kinase C zeta. It contains an actin binding site and an ATP binding site and is most closely related to twinfilin (PTK9), a conserved actin monomer binding protein. TWF2 is an actin binding protein involved in motile and morphological processes. It inhibits actin polymerization, likely by sequestering G actin. By capping the barbed ends of filaments, it also regulates motility. It seems to play an important role in clathrin mediated endocytosis and distribution of endocytic organelles.
Images
 | Western blot analysis of TWF2 (GB113521) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |