| Reactivity: | M | 
| Applications: | WB | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Full Name: | UBE2O rabbit polyclonal antibody  | 
Gene Name:  | (E3-independent) E2 ubiquitin-conjugating enzyme UBE2O  | 
Synonyms:  | E2/E3 hybrid ubiquitin-protein ligase UBE2O, Ubiquitin-conjugating enzyme E2 O, Ubiquitin-conjugating enzyme E2 of 230 kDa, Ubiquitin-protein ligase O, Ube2o, Kiaa1734, Ubiquitin carrier protein O  | 
Immunogen:  | Recombinant protein corresponding to Mouse UBE2O  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Predicted MW.  | 141 kDa  | 
Observed MW.  | 220 kDa  | 
Uniprot ID:  | Q6ZPJ3  | 
Product Usage Information
Applications  | Species  | Dilution  | Positive tissue  | 
WB  | Mouse  | 1: 500-1: 1000  | brain, skeletal muscle  | 
Background
UBE20, also known as E2-230K, is a 1,292 amino acid member of the uniquitin-conjugating enzyme family that is involved in protein modification. Expressed predominately in heart and skeletal muscle, UBE2O functions to catalyze the ATP-dependent covalent attachment of ubiquitin to select proteins, thereby targeting the ubiquitinated proteins for proteasomal degradation.
Images
![]()  | Western blot analysis of UBE2O (GB112665) at dilution of 1: 500  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |