| Reactivity: | M & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | WDR13 rabbit polyclonal antibody |
Gene Name: | WD repeat-containing protein 13 |
Synonyms: | Wdr13, located at OATL1, MG21 |
Immunogen: | Recombinant protein corresponding to Mouse WDR13 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 54 kDa |
Observed MW. | 54 kDa |
Uniprot ID: | Q91V09 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 1000-1: 2000 | lung, heart, kidney |
IHC/IF | Mouse, Rat | 1: 2500-1: 8000 | lung |
Background
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. A similar protein in mouse is thought to be a negative regulator of the pancreatic beta cell proliferation. Mice lacking this gene exhibit increased pancreatic islet mass and higher serum insulin levels, and are mildly obese.
Images
| Western blot analysis of WDR13 (GB112602) at dilution of 1: 1000 |
| Immunohistochemistry of paraffin embedded mouse lung using WDR13 (GB112602) at dilution of 1: 2500 (400x lens) |
| Immunohistochemistry of paraffin embedded rat lung using WDR13 (GB112602) at dilution of 1: 2500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |