Adenovirus CBFA2T1 (200 μl)

Adenovirus CBFA2T1 (200 μl)

Cat. #: M1128
Availability: In Stock
$685.00
-+
Product Category:   Human Adenovirus Type5 (dE1/E3) expressing Core-binding Factor, Runt Domain, Alpha Subunit 2; Translocated To, 1; Cyclin D-related under a CMV promoter.
Description:   Core-binding Factor, Runt Domain, Alpha Subunit 2; Translocated To, 1; Cyclin D-related, pre-packaged adenovirus, ready to ship and ready to use format.
Gene:   Core-binding Factor, Runt Domain, Alpha Subunit 2; Translocated To, 1; Cyclin D-related
NCBI Acc. #:   BC005850
Gene ID:   862
GI Number:   13543377
Fusion Tag:   C-terminus V5 epitope tag
Promoter:   CMV
Titer:   1x1010~1x1011 PFU/ml
Storage Buffer:   DMEM with 2.5% BSA, 2.5% glycerol
Background:   CBFA2T1 gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.
Documents:   Request a manual/MSDS

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