Publications

Over the past 8 years, LifeSct LLC have provided a large number of high-quality products and services to life scientists around the world. Please click to view the publications referring LifeSct's products and services.

1. Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in monkeys. 
Publication: Cell        Product: LiFect293™ Transfection Reagent

2. Rapid 40S scanning and its regulation by mRNA structure during eukaryotic translation initiation. 
Publication: Cell        Product: Gene Synthesis

1. A multiclade env–gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques. 
Publication: Nature Medicine        Product: LiFect293™ Transfection Reagent

2. HLA class I signal peptide polymorphism determines the level of CD94/NKG2–HLA-E-mediated regulation of effector cell responses. 
Publication: Nature Immunology        Service: Gene Synthesis

1. mRNA decapping activators Pat1 and Dhh1 regulate transcript abundance and translation to tune cellular responses to nutrient availability. 
Publication: Nucleic Acids Research        Product: 2× ExSembly™ Cloning Master Mix

2. Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD. 
Publication: Nature Communications        Product: 2× LiTaq™ PCR Master Mix (+Dye)

3. Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms. 
Publication: Molecular Cell        Product: 2× LiTaq™ PCR Master Mix (+Dye)

4. eEF2 diphthamide modification restrains spurious frameshifting to maintain translational fidelity. 
Publication: Nucleic Acids Research        Service: Gene Synthesis

1. Increased neutralization potency and breadth elicited by a SARS-CoV-2 mRNA vaccine forming virus-like particles. 
Publication: PNAS        Product: LiFect293™ Transfection Reagent

2. O-GlcNAc Transferase is Required to Maintain Satellite Cell Function.  
Publication: Stem Cells        Product: PeneFect™ Transfection Reagent

3. HLA class-I-peptide stability mediates CD8+ T cell immunodominance hierarchies and facilitates HLA associated immune control of HIV.  
Publication: Cell Report        Service: Gene Synthesis

4. Inhibition of KDM5A attenuates cisplatin-induced hearing loss via regulation of the MAPK/AKT pathway. 
Publication: Cellular and Molecular Life Sciences        Product: Rhodamine 123

5. YAP/TEAD1 Complex Is a Default Repressor of Cardiac Toll-Like Receptor Genes. 
Publication: International Journal of Molecular Sciences        Product: LiQuant™ Universal Green qPCR Master Mix

6. Metabolic changes accompanying the loss of fumarate hydratase and malate–quinone oxidoreductase in the asexual blood stage of Plasmodium falciparum. 
Publication: JBC        Service: Gene Synthesis

7. Knockdown of lncRNA TP53TG1 Enhances the Efficacy of Sorafenib in Human Hepatocellular Carcinoma Cells. 
Publication: non-coding RNA        Product: LiQuant™ Universal Green qPCR Master Mix

8. Creating and Validating Ligase Primers to Detect Single Nucleotide Polymorphisms Associated with Atovaquone Resistance in Plasmodium falciparum. 
Publication: ASTMH        Service: Gene Synthesis

9. Genetic and enzymatic characterization of Amy13E from Cellvibrio japonicus reclassifies it as a cyclodextrinase also capable of α-diglucoside degradation. 
Publication: ASM        Product: 2× ExSembly™ Cloning Master Mix

10. Yeast eIF2A has a minimal role in translation initiation and uORF-mediated translational control in vivo. 
Publication: bioRxiv        Service: Gene Synthesis

11. Live-attenuated pediatric parainfluenza vaccine expressing 6P-stabilized SARS-CoV-2 spike protein is protective against SARS-CoV-2 variants in hamsters. 
Publication: PLOS        Product: LiFect293™ Transfection Reagent

12. Functional Anatomy of the Trimer Apex Reveals Key Hydrophobic Constraints That Maintain the HIV-1 Envelope Spike in a Closed State. 
Publication: ASM        Product: LiFect293™ Transfection Reagent

13. Redesigned TetR-Aptamer System To Control Gene Expression in Plasmodium falciparum. 
Publication: ASM        Service: Gene Synthesis

14. Redesigned TetR-Aptamer System To Control Gene Expression in Plasmodium falciparum. 
Publication: BBRC        Service: Gene Synthesis

15. Selectively expressing SARS-CoV-2 Spike protein S1 subunit in cardiomyocytes induces cardiac hypertrophy in mice. 
Publication: bioRxiv        Product: LiQuant™ Universal Green qPCR Master Mix

16. Predominant Founder Effect among Recurrent Pathogenic Variants for an X-Linked Disorder. 
Publication: Genes        Service: Gene Synthesis

17. Diversity and Complexity of the Large Surface Protein Family in the Compacted Genomes of Multiple Pneumocystis Species. 
Publication: ASM        Product: LiSpark™ Max SuFi PCR Master Mix

18. Neuropathy target esterase activity predicts retinopathy among PNPLA6 disorders. 
Publication: bioRxiv        Service: Gene Synthesis

19. In Vitro Analysis of Rationally Designed Multimerization Sequences. 
Publication: ProQuest        Product: LiTaq™ Plus PCR Master Mix (+Dye)

20. Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine candidate is protective in macaques. 
Publication: bioRxiv        Product: LiFect293™ Transfection Reagent

1. Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in monkeys. 
Publication: Cell        Product: LiFect293™ Transfection Reagent

2. A multiclade env–gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques. 
Publication: Nature Medicine        Product: LiFect293™ Transfection Reagent

3. mRNA decapping activators Pat1 and Dhh1 regulate transcript abundance and translation to tune cellular responses to nutrient availability. 
Publication: Nucleic Acids Research        Product: 2× ExSembly™ Cloning Master Mix

4. Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD. 
Publication: Nature Communications        Product: 2× LiTaq™ PCR Master Mix (+Dye)

5. Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms. 
Publication: Molecular Cell        Product: 2× LiTaq™ PCR Master Mix (+Dye)

6. Increased neutralization potency and breadth elicited by a SARS-CoV-2 mRNA vaccine forming virus-like particles. 
Publication: PNAS        Product: LiFect293™ Transfection Reagent

7. O-GlcNAc Transferase is Required to Maintain Satellite Cell Function.  
Publication: Stem Cells        Product: PeneFect™ Transfection Reagent

8. Inhibition of KDM5A attenuates cisplatin-induced hearing loss via regulation of the MAPK/AKT pathway. 
Publication: Cellular and Molecular Life Sciences        Product: Rhodamine 123

9. YAP/TEAD1 Complex Is a Default Repressor of Cardiac Toll-Like Receptor Genes. 
Publication: International Journal of Molecular Sciences        Product: LiQuant™ Universal Green qPCR Master Mix

10. Knockdown of lncRNA TP53TG1 Enhances the Efficacy of Sorafenib in Human Hepatocellular Carcinoma Cells. 
Publication: non-coding RNA        Product: LiQuant™ Universal Green qPCR Master Mix

11. Genetic and enzymatic characterization of Amy13E from Cellvibrio japonicus reclassifies it as a cyclodextrinase also capable of α-diglucoside degradation. 
Publication: ASM        Product: 2× ExSembly™ Cloning Master Mix

12. Live-attenuated pediatric parainfluenza vaccine expressing 6P-stabilized SARS-CoV-2 spike protein is protective against SARS-CoV-2 variants in hamsters. 
Publication: PLOS        Product: LiFect293™ Transfection Reagent

13. Functional Anatomy of the Trimer Apex Reveals Key Hydrophobic Constraints That Maintain the HIV-1 Envelope Spike in a Closed State. 
Publication: ASM        Product: LiFect293™ Transfection Reagent

14. Selectively expressing SARS-CoV-2 Spike protein S1 subunit in cardiomyocytes induces cardiac hypertrophy in mice. 
Publication: bioRxiv        Product: LiQuant™ Universal Green qPCR Master Mix

15. Diversity and Complexity of the Large Surface Protein Family in the Compacted Genomes of Multiple Pneumocystis Species. 
Publication: ASM        Product: LiSpark™ Max SuFi PCR Master Mix

16. In Vitro Analysis of Rationally Designed Multimerization Sequences. 
Publication: ProQuest        Product: LiTaq™ Plus PCR Master Mix (+Dye)

17. Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine candidate is protective in macaques. 
Publication: bioRxiv        Product: LiFect293™ Transfection Reagent

1. Rapid 40S scanning and its regulation by mRNA structure during eukaryotic translation initiation. 
Publication: Cell        Service: Gene Synthesis

2. HLA class I signal peptide polymorphism determines the level of CD94/NKG2–HLA-E-mediated regulation of effector cell responses. 
Publication: Nature Immunology        Service: Gene Synthesis

3. eEF2 diphthamide modification restrains spurious frameshifting to maintain translational fidelity. 
Publication: Nucleic Acids Research        Service: Gene synthesis

4. HLA class-I-peptide stability mediates CD8+ T cell immunodominance hierarchies and facilitates HLA associated immune control of HIV.  
Publication: Cell Report        Service: Gene Synthesis

5. Metabolic changes accompanying the loss of fumarate hydratase and malate–quinone oxidoreductase in the asexual blood stage of Plasmodium falciparum. 
Publication: JBC        Service: Gene synthesis

6. Creating and Validating Ligase Primers to Detect Single Nucleotide Polymorphisms Associated with Atovaquone Resistance in Plasmodium falciparum. 
Publication: ASTMH        Service: Gene Synthesis

7. Yeast eIF2A has a minimal role in translation initiation and uORF-mediated translational control in vivo. 
Publication: bioRxiv        Service: Gene Synthesis

8. Redesigned TetR-Aptamer System To Control Gene Expression in Plasmodium falciparum. 
Publication: ASM        Service: Gene Synthesis

9. Redesigned TetR-Aptamer System To Control Gene Expression in Plasmodium falciparum. 
Publication: BBRC        Service: Gene Synthesis

10. Predominant Founder Effect among Recurrent Pathogenic Variants for an X-Linked Disorder. 
Publication: Genes        Service: Gene Synthesis

11. Neuropathy target esterase activity predicts retinopathy among PNPLA6 disorders. 
Publication: bioRxiv        Service: Gene Synthesis


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