Adenovirus EPO (200 µl)

Adenovirus EPO (200 µl)

Cat. #: M1103
Availability: In Stock
$685.00
-+
Product Category:   Human Adenovirus Type5 (dE1/E3) expressing human Erythropoietin (EPO).
Description:   Erythropoietin, pre-made adenovirus, ready to ship and ready to use format.
Gene:   Erythropoietin
NCBI Acc. #:   BC000340
Gene ID:   55854
GI Number:   18088891
Fusion Tag:   No
Promoter:   CMV
Titer:   1x1010~1x1011 PFU/ml
Storage Buffer:   DMEM with 2.5% BSA, 2.5% glycerol
Background:   Erythropoietin (EPO) protein is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. EPO is not responsible for early commitment to the lineage, and instead induces the final maturation of partially differentiated erythroid cells and the production of red cell-specific proteins, such as hemoglobin. The EPO receptor (EPOR) is present in higher levels on precursor cells, and expression diminishes with cell maturation.Hepatocytes are the main source of EPO in the fetus, followed by interstitial cells of the kidney after birth and through adulthood. EPO expression is upregulated during hypoxia, and low levels of transcription have also been detected in lung and brain tissue under these conditions. Recent data suggest that EPO may also play a role in the protection of neuronal tissue from damage and initiation of repair.
Documents:   Request a manual/MSDS

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