Adenovirus SDC1 (200 μl)

Adenovirus SDC1 (200 μl)

Cat. #: M1326
Availability: In Stock
$685.00
-+
Product Category:   Human Adenovirus Type5 (dE1/E3) expressing Human syndecan 1.
Description:   Pre-made adenovirus for over-expression of Human syndecan 1, ready to ship and ready to use format.
Gene:   Syndecan 1
NCBI Acc. #:   BC008765
Gene ID:   6382
GI Number:   14250611
Fusion Tag:   No
Promoter:   CMV
Titer:   1×1010~1×1011 PFU/ml
Storage Buffer:   DMEM with 2.5% BSA, 2.5% glycerol
Background:   CD138 (syndecan 1, SDC1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
Storage:   -80°C
Documents:   Request a manual/MSDS

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