Adenovirus CLDN19 (200 μl)

Adenovirus CLDN19 (200 μl)

Cat. #: M1288
Availability: In Stock
Product Category:   Human Adenovirus Type5 (dE1/E3) expressing Claudin 19 under a CMV promoter.
Description:   Claudin 19, pre-packaged adenovirus, ready to ship and ready to use format.
Gene:   Claudin 19
NCBI Acc. #:   BC030524.1
Gene ID:   9634
GI Number:   149641
Fusion Tag:   Fusion with V5 tag at C-terminal
Promoter:   CMV
Titer:   1×1010~1×1011 PFU/ml
Storage Buffer:   DMEM with 2.5% BSA, 2.5% glycerol
Background:   The product of the Claudin 19 gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Storage:   -80°C
Documents:   Request a manual/MSDS

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