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|Product Category:||Human Adenovirus Type5 (dE1/E3) expressing Carnitine Palmitoyltransferase 1A (liver) (CPT1A) under a CMV promoter.|
|Description:||Carnitine Palmitoyltransferase 1A (liver), pre-packaged adenovirus, ready to ship and ready to use format.|
|Gene:||Carnitine Palmitoyltransferase 1A (liver)|
|NCBI Acc. #:||BC000185|
|Storage Buffer:||DMEM with 2.5% BSA, 2.5% glycerol|
|Background:||The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.|
|Documents:||Request a manual/MSDS|