Adenovirus CPT1A (200 μl)

Adenovirus CPT1A (200 μl)

Cat. #: M1223
Availability: In Stock
Product Category:   Human Adenovirus Type5 (dE1/E3) expressing Carnitine Palmitoyltransferase 1A (liver) (CPT1A) under a CMV promoter.
Description:   Carnitine Palmitoyltransferase 1A (liver), pre-packaged adenovirus, ready to ship and ready to use format.
Gene:   Carnitine Palmitoyltransferase 1A (liver)
NCBI Acc. #:   BC000185
Gene ID:   1374
GI Number:   12652864
Fusion Tag:   No
Promoter:   CMV
Titer:   1x1010~1x1011 PFU/ml
Storage Buffer:   DMEM with 2.5% BSA, 2.5% glycerol
Background:   The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Documents:   Request a manual/MSDS

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