Adenovirus NEUROG1 (200 μl)

Adenovirus NEUROG1 (200 μl)

Cat. #: M1115
Availability: In Stock
Description:   This recombinant human adenovirus type 5 (dE1/E3) expresses human Neurogenin 1 (NEUROG1) under CMV promoter.
Gene:   Neurogenin 1
NCBI Acc. #:   NM_006161
Gene ID:   4762
GI Number:   5453769
Fusion Tag:   C-terminus V5 epitope tag
Promoter:   CMV
Titer:   1x1010~1x1011 PFU/ml
Storage Buffer:   DMEM with 2.5% BSA, 2.5% glycerol
Background:   Neurogenin 1 is a basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.
Documents:   Request a manual/MSDS

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