Adenovirus UHRF1 (200 μl)

Adenovirus UHRF1 (200 μl)

Cat. #: M1163
Availability: In Stock
$685.00
-+
Product Category:   Human Adenovirus Type5 (dE1/E3) expressing human Ubiquitin-like, Containing PHD And RING Finger Domains, 1 (UHRF1).   
Description:   Pre-made adenovirus for over-expression of human Ubiquitin-like, Containing PHD And RING Finger Domains, 1 (UHRF1), ready to ship and ready to use format.
Gene:   Ubiquitin-like, Containing PHD And RING Finger Domains, 1
NCBI Acc. #:   BC113875
Gene ID:   29128
GI Number:   88683008
Fusion Tag:   C-terminus V5 tag
Promoter:   CMV
Titer:   1x1010~1x1011 PFU/ml
Storage Buffer:   DMEM with 2.5% BSA, 2.5% glycerol
Background:   UHRF1 gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.
Documents:   Request a manual/MSDS

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